A Spanish scientist has opened the way to a new understanding of what causes metastasis in cancer cells. The study which took place at IRB Barcelona has identified the cells responsible for initiating and promoting metastasis in a bunch of different types of human tumors.
But what is metastasis? Cancer metastasis is the spread of cancer cells to tissues and organs beyond where the tumor originated and the formation of new tumors, and is the single event that results in the death of most patients with cancer (2).
Fat intake and CD36
In the study, mice given a high-fat diet (specifically, palmitic acid) developed the most aggressive metastases. This allowed researchers to conclude that fat intake could enhance the metastasis process. In the absence of the CD36 protein, the human tumors analyzed did not develop metastasis. Further, the inhibition of this protein also dramatically reduced the size of existing metastases. (1).
The researchers discovered the metastatic CD36 cells in samples of patients with oral cancer with different degrees of aggressiveness. Of the tumors analyzed, very few were found to have the capacity for metastasis, but with the addition of CD36 it made tumors metastatic. Further, the effect witnessed by the team of CD36 in cancer cells is similar in melanoma cells, luminal breast cancer cells, ovarian, bladder and lung cancer.
Researchers agree that even though tests have not been done in all forms of cancer, they can state that CD36 is a general marker for metastasis of cells. This will allow further research to be done on the CD36 protein and to determine the distribution of metastasis in the cancer cells, and to determine where they anchor to when they leave it, or why they are so sensitive to fat (1).
When mice were provided with a high-fat diet (fifteen percent higher than normal, mimicking a so-called cafeteria diet) and inoculated with a type of oral cancer. Usually, the inoculation would amount to 30% of animals developing metastasis, but with a much higher amount of fat in the blood, around 80% of the mice developed numerous and large metastases (1).
Study conclusions
The protein CD36, which absorbs fat from the cell membrane, is an essential factor that determines whether tumor cells become metastatic (1). Further, they found that there appears to be a direct link between fat intake and an increase in metastatic potential through CD36 (1). The IRB Barcelona team is looking to develop antibodies against CD36 with the potential to treat metastasis in cancer patients.
The researchers have opened new doorways when it comes to cancer treatment, a treatment that will dramatically decrease the chances of metastasis in cancer patients. Even though the research was only done on mice, the possibilities for the future are endless. In some time we could end up having therapies that prevent metastases from developing and will help save lives.
There is a good news to fight formation of free radicals in your body. Read below what you need to know about C24/7.
The good news is, C24/7 and COMPLETE PHYTOENERGIZER are your saving companion.. It contains 12 Digestive Enzymes that are essential to the body because good health is heavily dependent on good digestion, and good digestion is totally dependent upon having sufficient enzymes in the body. Vitamins, minerals, and hormones must have enzymes to work properly. These enzymes are also needed for breaking down the fats in the body.
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A breakthrough product from Nature's Way, and is exclusively distributed by Alliance in Motion Global. It has a very high ORAC (Oxygen Radical Absorbance Capacity) value.
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1. Approximately 22,000 Antioxidants and Phytonutrients
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The broad spectrum of nutrients in this mixture is essential to health, vitality and energy.
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Chlorophyll, the green coloring pigment of the plant, was discovered as very beneficial because it is a good source of antioxidant.
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According to studies, the mother of all kinds of diseases is constipation. The waste left in our intestines becomes toxins that cause different kinds of diseases. Good health is dependent upon good digestion.
These enzymes are essential to the body because good health is heavily dependent on good digestion, and good digestion is totally dependent upon having sufficient enzymes in the body. Vitamins, minerals, and hormones must have enzymes to work properly. These enzymes are also needed for breaking down the fats in the body.
8. 10 Essential Fatty Acids
It has Omega Oil 3 and 6 that dissolves harmful fatty deposits.
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10. 18 Amino Acids
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This formula helps in the disintegration of vitamin C in the body. The Bioflavonoids come from all natural sources particularly Lemon, Orange, Grapefruit, Lime and Tangerine.
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Cysteine Hydrochloride - An amino acid known to detoxify the liver and counter the negative effect of alcohol (such as Liver Damage and Hangover)
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Japanese Knotweed - An excellent source of Resveratrol
Premium Red Wine Extract - Lengthens human Lifespan
Grape Seed Extract - An excellent anti-oxidant Lengthens human Lifespan
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C24/7 Technology
PHYTO-ALKATECH: A powerful complex of natural alkaline ingredients designed to enhance the alkalinity of this formulation and also to protect and neutralize possible acid damage when it reaches the stomach. It preserves the purity and potency of this natura-ceuticals.
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